The first 1000 days and a resilient life course

Reducing inequality of opportunity through an optimal start for every child

The first 1000 days of a child are crucial for the entire life course. The environment in which mother and child find themselves can have an impact on the health and well-being of the child, also later in life. Examples of environmental factors are the physical place of residence, a small social network, an unhealthy lifestyle and severe stress. Negative consequences of these factors increase the chance of poorer health at birth and can even be passed on to subsequent generations. In this way, inequality of opportunity is maintained intergenerationally.

To tackle intergenerational inequality of opportunity, we enlist social and medical support. Fragmented supply hinders timely care. Our goal is to give every child an optimal start and break cycles. We use integrated care, co-creation, education, and research. We promote reproductive and parenting appreciation, better leave arrangements, and childcare, while monitoring social impact of the activities.

Resources

Scientific publications

  • Blaauwendraad SM, Kamphuis ASJ, Javier Ruiz-Ojeda F, Brandimonte-Hernández M, Flores-Ventura E, Abrahamse-Berkeveld M, Collado MC, van Diepen JA, Iozzo P, Knipping K, van Loo-Bouwman CA, Gil Á, Gaillard R. Risk Factors in the First 1000 Days of Life Associated With Childhood Obesity: A Systematic Review and Risk Factor Quality Assessment. Obes Rev. 2026 Feb;27(2):e70025. doi: 10.1111/obr.70025. Epub 2025 Nov 19. PMID: 41261882. [Link]
  • Boxem, A. J., Blaauwendraad, S. M., Mulders, A. G. M. G. J., Bekkers, E. L., Gaillard, R., & Jaddoe, V. W. V. (2025). Age among women and men, time to pregnancy and risk of miscarriage. BMC Medicine, 23(1), 639. https://doi.org/10.1186/s12916-025-04462-8 [Link]
  • Boxem A.J., Mulders A.G.M.G.J. , van Rossum I., Bekkers E. L., Gaillard R, Jaddoe V. W. V. (2025) Poverty and Social Disadvantage in Women and Men and Fertility Outcomes. JAMA Netw Open. ;8(9):e2532741. doi:10.1001/jamanetworkopen.2025.32741 [Link]

Core team

Romy Gaillard (Erasmus MC), Fernando Secomandi (TUD), Kebede Haile Misgina (Erasmus MC), Anne Boxem (Erasmus MC), Sushma Munshi (Erasmus MC), Hilmar Bijma (Erasmus MC), Igna Bonfrer (EUR), Jan-Carel Diehl (TUD), Mijke Lambregtse-van den Berg (Erasmus MC), Tanja Houweling (Erasmus MC) en Vincent Jaddoe (Erasmus MC).

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